The US scientist Richard F. Heck and the Japanese chemists Ei-ichi Negishi and Akira Suzuki were recently awarded the 2010 Nobel Prize for Chemistry for their palladium-catalyzed coupling of carbon atoms („C-C Coupling Reaction“).
Today such coupling reactions by homogeneous palladium catalysis are already used for the manufacture of high-value organics on an industrial scale: e.g. biphenyls for anti-cancer specialties, for antibiotics, or for polymers in light-emitting organic diodes (PLEDs).
For decades our Chemical Products Business Unit has been manufacturing suitable homogeneous palladium catalysts and their precursors as core products.
For the growing market of homogeneous catalysis Heraeus early invested into the latest plants and capacity expansions for the manufacture of such “Organometallics”.
These are highly sophisticated compounds like
Dichloro[1,1'-ferrocenylbis(diphenylphosphane)]palladium(II) dichloromethane,
which are used as homogeneous catalysts for highly selective C-C coupling reactions, e.g. of Grignard reagents with vinyl or aryl halides.
Unlike standard palladium catalysis, such innovative chemical syntheses avoid side-products.
Heraeus is your partner for coupling catalysis!
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